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Barack Obama was always going to have a place in history as the first African-American president. That's no small feat given the nation's peculiar past. But achieving what other Democratic presidents couldn't fueled deep divisions within the country and set the table for a second term with daunting challenges.

An experimental antiviral drug shows promise fighting COVID-19. Also a next-generation Coronavirus test raises hopes and concerns. And, the Navy imposes strict rules on a branch of civilian mariners.

Uganda is challenging morphine's reputation as an archaic, dangerous drug — and inspiring other African countries to do the same.

This week, we're listening back to some favorite Fresh Air interviews from the past decade. The bandleader for The Late Show with Stephen Colbert let loose at the piano during this 2018 interview.

Rapinoe has also been an outspoken advocate for pay equity and the Black Lives Matter movement. "I see patriotism as constantly demanding better of ourselves," she says. Her new book is One Life.

Schools were shut when the novel coronavirus first became a concern. Here's how Hong Kong handled re-opening — and now, a second closing due to a spike in cases.

Just six months ago, Biden's campaign seemed all but over. But in the end, he had just enough connection, through his oft-mentioned ties to Obama and other key Democrats, to overcome his deficits.

A new collaboration from Karen O and Danger Mouse, a fresh new beat from French producer FKJ and a new single from Jack White's The Raconteurs are among this month's favorites.

More than 200 migrants die attempting to cross the Southwest border each year. Slowly, scientists at a Texas laboratory are seeking the story of their bones.

Clemson walloped the University of Alabama in college football's national championship last season. Now perennial powerhouse Alabama is trying to learn from the loss.